Overview
Innovative testing of new raw materials and products can be conducted using the OMICA Skin. This platform is designed to provide the Full-Thickness Skin Model. One of the key advantages is its enhanced predictive capability in comparison to conventional in-vitro methods. This is due to the fact that human skin cells are used in a three-dimensional environment, resulting in a more accurate representation of native human skin.
Description
The OMICA Skin Model comprises of a fully developed epidermis, which is the outer layer of the skin, and a dermis layer underneath that contains natural connective tissue based on collagen. As a result, the model mimics several anatomical and physiological characteristics of native human skin, making it an excellent resource for both research endeavors and the creation of novel, alternate testing methods.
Aim
This skin irritation test platform offers an evaluation of the epidermal damage over a period of time, leading to a comprehensive categorization of Severe, Moderate, Mild or Minimal / Non-Irritant. By employing the ET50 technique, it is possible to rank ingredients or formulations in terms of their irritation potential or compare them with the standards prevalent in the industry. Our protocols and epidermal models are specifically developed for non-regulatory purposes, with the aim of labeling and categorizing chemicals based on their in vitro skin irritation evaluation. However, if the test substance is deemed irritant, there may be a need for an additional in vitro skin corrosion test using the OECD test guidelines to supplement the generated data.
